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Inhibition of telomerase activity by HDV ribozyme in cancers
BACKGROUND: Telomerase plays an important role in cell proliferation and carcinogenesis and is believed to be a good target for anti-cancer drugs. Elimination of template function of telomerase RNA may repress the telomerase activity. METHODS: A pseudo-knotted HDV ribozyme (g.RZ57) directed against...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024244/ https://ncbi.nlm.nih.gov/pubmed/21208462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-1 |
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