Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim

The proapoptotic Bcl2 homology domain 3(BH3)-only protein Bim is controlled by stringent post-translational regulation, predominantly through alterations in phosphorylation status. To identify new kinases involved in its regulation, we carried out a yeast two-hybrid screen using a non-spliceable var...

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Detalhes bibliográficos
Main Authors: Moujalled, Diane, Weston, Ross, Anderton, Holly, Ninnis, Robert, Goel, Pranay, Coley, Andrew, Huang, David CS, Wu, Li, Strasser, Andreas, Puthalakath, Hamsa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024128/
https://ncbi.nlm.nih.gov/pubmed/21151042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.190
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