An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasia

Multiple epiphyseal dysplasia (MED) can result from mutations in matrilin-3, a structural protein of the cartilage extracellular matrix. We have previously shown that in a mouse model of MED the tibia growth plates were normal at birth but developed a progressive dysplasia characterised by the intra...

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Hlavní autoři: Nundlall, Seema, Rajpar, M. Helen, Bell, Peter A., Clowes, Christopher, Zeeff, Leo A. H., Gardner, Benjamin, Thornton, David J., Boot-Handford, Raymond P., Briggs, Michael D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2010
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024081/
https://ncbi.nlm.nih.gov/pubmed/20428984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-010-0193-y
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