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The unfolded protein response and its relevance to connective tissue diseases
The unfolded protein response (UPR) has evolved to counter the stresses that occur in the endoplasmic reticulum (ER) as a result of misfolded proteins. This sophisticated quality control system attempts to restore homeostasis through the action of a number of different pathways that are coordinated...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784867/ https://ncbi.nlm.nih.gov/pubmed/19851784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-009-0877-8 |
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