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Strategies for diminishing katanin-based loss of microtubules in tauopathic neurodegenerative diseases

It is commonly stated that microtubules gradually disintegrate as tau becomes dissociated from them in tauopathies such as Alzheimer's disease. However, there has been no compelling evidence to date that such disintegration is due to depolymerization of microtubules from their ends. In recent s...

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Detalhes bibliográficos
Main Authors: Sudo, Haruka, Baas, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024046/
https://ncbi.nlm.nih.gov/pubmed/21118899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq521
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