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Use of Yeast Chemigenomics and COXEN Informatics in Preclinical Evaluation of Anticancer Agents
Bladder cancer metastasis is virtually incurable with current platinum-based chemotherapy. We used the novel COXEN informatic approach for in silico drug discovery and identified NSC-637993 and NSC-645809 (C1311), both imidazoacridinones, as agents with high-predicted activity in human bladder cance...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Neoplasia Press Inc.
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023847/ https://ncbi.nlm.nih.gov/pubmed/21253455 |
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