טוען...
Transcription and replication: Breaking the rules of the road causes genomic instability
Replication and transcription machineries progress at high speed on the same DNA template, which inevitably causes traffic accidents. Problems are not only caused by frontal collisions between polymerases, but also by cotranscriptional R-loops. These RNA-DNA hybrids induce genomic instability by blo...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Landes Bioscience
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023637/ https://ncbi.nlm.nih.gov/pubmed/21326900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.1.2.12665 |
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