Unsaturated FAs prevent palmitate-induced LOX-1 induction via inhibition of ER stress in macrophages

Palmitic acid (PA) upregulates oxidized LDL receptor-1 (LOX-1), a scavenger receptor responsible for uptake of oxidized LDL (oxLDL), and enhances oxLDL uptake in macrophages. However, the precise underlying mechanism remains to be elucidated. PA is known to induce endoplasmic reticulum (ER) stress i...

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Detaylı Bibliyografya
Asıl Yazarlar: Ishiyama, Junichi, Taguchi, Ryoko, Akasaka, Yunike, Shibata, Saiko, Ito, Minoru, Nagasawa, Michiaki, Murakami, Koji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2011
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023550/
https://ncbi.nlm.nih.gov/pubmed/21078775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M007104
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