Inhibition of Proprotein Convertase SKI-1 Blocks Transcription of Key Extracellular Matrix Genes Regulating Osteoblastic Mineralization

Mineralization, a characteristic phenotypic property of osteoblastic lineage cells, was blocked by 4-(2-aminoethyl) benzenesulfonyl fluoride hydrochloride (AEBSF) and decanoyl-Arg-Arg-Leu-Leu-chloromethyl ketone (dec-RRLL-cmk), inhibitors of SKI-1 (site 1; subtilisin kexin like-1) protease. Because...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gorski, Jeff P., Huffman, Nichole T., Chittur, Sridar, Midura, Ronald J., Black, Claudine, Oxford, Julie, Seidah, Nabil G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023479/
https://ncbi.nlm.nih.gov/pubmed/21075843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.151647
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados