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The src phosphorylation of its epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers

PURPOSE: The frequently elevated activities of the c-src and c-yes products in human epithelial tumors suggest that these activated tyrosine kinases have tumorigenic functions analogous to the v-src and v-yes oncogene products. Studies of v-src transformed fibroblasts have identified many of the eff...

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Detalhes bibliográficos
Principais autores: Wong, Ching Hang, Baehner, Frederick L., Spassov, Danislav S., Ahuja, Deepika, Wang, Donghui, Hann, Byron, Blair, Jimmy, Shokat, Kevan, Welm, Alana L., Moasser, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023342/
https://ncbi.nlm.nih.gov/pubmed/19318475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2533
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