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The Structural Features of Trask That Mediate Its Anti-Adhesive Functions
Trask/CDCP1 is a transmembrane protein with a large extracellular and small intracellular domains. The intracellular domain (ICD) undergoes tyrosine phosphorylation by Src kinases during anchorage loss and, when phosphorylated, Trask functions to inhibit cell adhesion. The extracellular domain (ECD)...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084758/ https://ncbi.nlm.nih.gov/pubmed/21559459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019154 |
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