Structure of a Conserved Retroviral RNA Packaging Element by NMR Spectroscopy and Cryo-Electron Tomography

The 5′-untranslated regions (5′-UTRs) of all gammaretroviruses contain a conserved “double hairpin motif” (Ψ(CD)) that is required for genome packaging. Both hairpins (SL-C and SL-D) contain GACG tetraloops that, in isolated RNAs, are capable of forming “kissing” interactions stabilized by two inter...

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Hauptverfasser: Miyazaki, Yasuyuki, Irobalieva, Rossitza N., Tolbert, Blanton, Smalls-Mantey, Adjoa, Iyalla, Kilali, Loeliger, Kelsey, D’Souza, Victoria, Khant, Htet, Schmid, Michael F., Garcia, Eric, Telesnitsky, Alice, Chiu, Wah, Summers, Michael F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023341/
https://ncbi.nlm.nih.gov/pubmed/20933521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.09.009
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