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Creation of “Humanized” Mice to Study Human Immunity

“Humanized” mice are a promising translational model for studying human hematopoiesis and immunity. Their utility has been enhanced by the development of new stocks of immunodeficient hosts, most notably mouse strains such as NOD-scid IL2rγ (null) mice that lack the IL-2 receptor common gamma chain....

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Autors principals: Pearson, Todd, Greiner, Dale L., Shultz, Leonard D.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023233/
https://ncbi.nlm.nih.gov/pubmed/18491294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142735.im1521s81
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