Wnt Signaling Requires the Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes

Canonical Wnt signaling requires inhibition of Glycogen Synthase Kinase 3 (GSK3) activity, but the molecular mechanism by which this is achieved remains unclear. Here we report that Wnt signaling triggers the sequestration of GSK3 from the cytosol into multivesicular bodies (MVBs), so that this enzy...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Taelman, Vincent F., Dobrowolski, Radoslaw, Plouhinec, Jean-Louis, Fuentealba, Luis C., Vorwald, Peggy P., Gumper, Iwona, Sabatini, David D., De Robertis, Edward M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022472/
https://ncbi.nlm.nih.gov/pubmed/21183076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.11.034
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars