Altered Intestinal Epithelial Homeostasis in Mice with Intestine-Specific Deletion of the Krüppel-Like Factor 4 Gene

The zinc finger transcription factor, Krüppel-like factor 4 (KLF4), is expressed in the post-mitotic, differentiated epithelial cells lining the intestinal tract and exhibits a tumor suppressive effect on intestinal tumorigenesis. Here we report a role for KLF4 in maintaining homeostasis of intestin...

Full description

Saved in:
Bibliographic Details
Main Authors: Ghaleb, Amr M., McConnell, Beth B., Kaestner, Klaus H., Yang, Vincent W.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022386/
https://ncbi.nlm.nih.gov/pubmed/21070761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.11.001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items