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Variation in amount of wild-type transthyretin in different fibril and tissue types in ATTR amyloidosis

Familial transthyretin (TTR) amyloidosis is caused by a mutation in the TTR gene, although wild-type (wt) TTR is also incorporated into the amyloid fibrils. Liver transplantation (LT) is the prevailing treatment of the disease and is performed in order to eliminate the mutant TTR from plasma. The ou...

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Autori principali: Ihse, Elisabet, Suhr, Ole B., Hellman, Ulf, Westermark, Per
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022153/
https://ncbi.nlm.nih.gov/pubmed/21107516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-010-0695-1
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