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Variation in amount of wild-type transthyretin in different fibril and tissue types in ATTR amyloidosis

Familial transthyretin (TTR) amyloidosis is caused by a mutation in the TTR gene, although wild-type (wt) TTR is also incorporated into the amyloid fibrils. Liver transplantation (LT) is the prevailing treatment of the disease and is performed in order to eliminate the mutant TTR from plasma. The ou...

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Detalhes bibliográficos
Main Authors: Ihse, Elisabet, Suhr, Ole B., Hellman, Ulf, Westermark, Per
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022153/
https://ncbi.nlm.nih.gov/pubmed/21107516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-010-0695-1
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