Mice Overexpressing the Gene for Heparin-Binding EGF-Like Growth Factor (HB-EGF) Have Increased Resistance to Hemorrhagic Shock and Resuscitation

BACKGROUND: The aim of the current study was to determine whether overexpression of HB-EGF could protect the intestines from injury after hemorrhagic shock and resuscitation (HS/R) in mice. METHODS: HS/R was induced in HB-EGF transgenic (TG) and wild type (WT) mice. CRM197 (5mg/kg) was administered...

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Hauptverfasser: Zhang, Hong-yi, Radulescu, Andrei, Chen, Chun-liang, Olson, Jacob K., Darbyshire, Amanda K., Besner, Gail E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022082/
https://ncbi.nlm.nih.gov/pubmed/20965535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.08.003
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