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Heparin-binding EGF-like Growth Factor Overexpression in Transgenic Mice Increases Resistance to Necrotizing Enterocolitis

BACKGROUND: Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency and the leading surgical cause of death in premature infants. We have shown that administration of exogenous heparin-binding EGF-like growth factor (HB-EGF) in protects the intestines from experimental NEC. The...

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Bibliografiske detaljer
Main Authors: Radulescu, Andrei, Zhang, Hong-Yi, Yu, Xiaoyi, Olson, Jacob K., Darbyshire, Amanda K., Chen, Yan, Besner, Gail E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953427/
https://ncbi.nlm.nih.gov/pubmed/20920709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2010.05.002
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