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Heparin-binding EGF-like Growth Factor (HB-EGF) Preserves Gut Barrier Function by Blocking Neutrophil-Endothelial Cell Adhesion after Hemorrhagic Shock and Resuscitation in Mice

BACKGROUND: We have shown that HB-EGF protects the intestines from injury in several different animal models including hemorrhagic shock and resuscitation (HS/R). The current study was designed to explore the mechanisms underlying the anti-inflammatory role of HB-EGF in preservation of gut barrier f...

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Detalhes bibliográficos
Main Authors: Zhang, Hong-yi, James, Iyore, Chen, Chun-Liang, Besner, Gail E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307915/
https://ncbi.nlm.nih.gov/pubmed/22153812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2011.10.001
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