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Light-Enhanced Catalysis by Pyridoxal Phosphate Dependent Aspartate Aminotransferase
The mechanisms of pyridoxal 5′-phosphate (PLP) dependent enzymes require substrates to form covalent “external aldimine” intermediates, which absorb light strongly between 410 nm and 430 nm. Aspartate aminotransferase (AAT) is a prototypical PLP dependent enzyme that catalyzes the reversible interco...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021986/ https://ncbi.nlm.nih.gov/pubmed/21058708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107054x |
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