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Light-Enhanced Catalysis by Pyridoxal Phosphate Dependent Aspartate Aminotransferase

The mechanisms of pyridoxal 5′-phosphate (PLP) dependent enzymes require substrates to form covalent “external aldimine” intermediates, which absorb light strongly between 410 nm and 430 nm. Aspartate aminotransferase (AAT) is a prototypical PLP dependent enzyme that catalyzes the reversible interco...

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Detalhes bibliográficos
Main Authors: Hill, Melissa P., Carroll, Elizabeth C., Vang, Mai C., Addington, Trevor A., Toney, Michael D., Larsen, Delmar S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021986/
https://ncbi.nlm.nih.gov/pubmed/21058708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107054x
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