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Coordinated Genome-Wide Modifications within Proximal Promoter Cis-regulatory Elements during Vertebrate Evolution

There often exists a “one-to-many” relationship between a transcription factor and a multitude of binding sites throughout the genome. It is commonly assumed that transcription factor binding motifs remain largely static over the course of evolution because changes in binding specificity can alter t...

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Detalhes bibliográficos
Main Authors: Yokoyama, Ken Daigoro, Thorne, Jeffrey L., Wray, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021792/
https://ncbi.nlm.nih.gov/pubmed/21118975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evq078
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