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Coordinated Genome-Wide Modifications within Proximal Promoter Cis-regulatory Elements during Vertebrate Evolution

There often exists a “one-to-many” relationship between a transcription factor and a multitude of binding sites throughout the genome. It is commonly assumed that transcription factor binding motifs remain largely static over the course of evolution because changes in binding specificity can alter t...

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書目詳細資料
Main Authors: Yokoyama, Ken Daigoro, Thorne, Jeffrey L., Wray, Gregory A.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021792/
https://ncbi.nlm.nih.gov/pubmed/21118975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evq078
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