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Posttranscriptional Regulation of MEK-1 by Polyamines through the RNA–binding Protein HuR Modulating Intestinal Epithelial Apoptosis
Mitogen-activated protein kinase kinase 1 (MEK-1) is an important signal transducing enzyme that is implicated in many aspects of cellular functions. Here, we report that cellular polyamines regulate MEK-1 expression at the posttranscriptional level through the RNA-binding protein HuR in intestinal...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021782/ https://ncbi.nlm.nih.gov/pubmed/20001965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091459 |
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