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Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function
Occludin is a transmembrane tight junction (TJ) protein that plays an important role in TJ assembly and regulation of the epithelial barrier function, but the mechanisms underlying its post-transcriptional regulation are unknown. The RNA-binding protein HuR modulates the stability and translation of...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3201881/ https://ncbi.nlm.nih.gov/pubmed/21745814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr567 |
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