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Polyamines Regulate c-Myc Translation through Chk2-dependent HuR Phosphorylation

All mammalian cells depend on polyamines for normal growth and proliferation, but the exact roles of polyamines at the molecular level remain largely unknown. The RNA-binding protein HuR modulates the stability and translation of many target mRNAs. Here, we show that in rat intestinal epithelial cel...

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Autori principali: Liu, Lan, Rao, Jaladanki N., Zou, Tongtong, Xiao, Lan, Wang, Peng-Yuan, Turner, Douglas J., Gorospe, Myriam, Wang, Jian-Ying
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785732/
https://ncbi.nlm.nih.gov/pubmed/19812253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-07-0550
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