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Translation of β-Globin m-RNA in β-Thalassemia and the S and C Hemoglobinopathies
Genetic and biochemical evidence indicates that in β-thalassemia there is impaired synthesis of the β-globin chains of hemoglobin A. In patients heterozygous for the hemoglobinopathies, hemoglobin S and hemoglobin C, the mutant β-chain is produced in smaller amounts than normal β(A). Defective m-RNA...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1972
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302135/ https://ncbi.nlm.nih.gov/pubmed/5009120 |
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