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Type 2 Metabotropic Glutamate Receptor (mGluR2) Fails to Negatively Couple to cGMP in Stably Transfected Cells
The group II metabotropic glutamate receptors 2 and 3 (mGluR2 and mGluR3) share sequence homology, common pharmacology and negative coupling to cAMP. We recently discovered that mGluR3 also is negatively coupled through a G-protein to the cGMP transduction pathway in rat cerebellar granule cells and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021184/ https://ncbi.nlm.nih.gov/pubmed/21115084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2010.11.012 |
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