Ischemia/Reperfusion Tolerance is Time-of-Day-Dependent: Mediation by the Cardiomyocyte Circadian Clock

RATIONALE: Cardiovascular physiology and pathophysiology vary dramatically over the course of the day. For example, myocardial infarction (MI) onset occurs with greater incidence during the early morning hours in humans. However, whether MI tolerance exhibits a time-of-day-dependence is unknown. OBJ...

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Bibliografiska uppgifter
Huvudupphovsmän: Durgan, David J., Pulinilkunnil, Thomas, Villegas-Montoya, Carolina, Garvey, Merissa E., Frangogiannis, Nikolaos G., Michael, Lloyd H., Chow, Chi-Wing, Dyck, Jason R.B., Young, Martin E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021132/
https://ncbi.nlm.nih.gov/pubmed/20007913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.209346
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