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Ischemia/Reperfusion Tolerance is Time-of-Day-Dependent: Mediation by the Cardiomyocyte Circadian Clock

RATIONALE: Cardiovascular physiology and pathophysiology vary dramatically over the course of the day. For example, myocardial infarction (MI) onset occurs with greater incidence during the early morning hours in humans. However, whether MI tolerance exhibits a time-of-day-dependence is unknown. OBJ...

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Main Authors: Durgan, David J., Pulinilkunnil, Thomas, Villegas-Montoya, Carolina, Garvey, Merissa E., Frangogiannis, Nikolaos G., Michael, Lloyd H., Chow, Chi-Wing, Dyck, Jason R.B., Young, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021132/
https://ncbi.nlm.nih.gov/pubmed/20007913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.209346
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