Ischemia/Reperfusion Tolerance is Time-of-Day-Dependent: Mediation by the Cardiomyocyte Circadian Clock

RATIONALE: Cardiovascular physiology and pathophysiology vary dramatically over the course of the day. For example, myocardial infarction (MI) onset occurs with greater incidence during the early morning hours in humans. However, whether MI tolerance exhibits a time-of-day-dependence is unknown. OBJ...

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Detalhes bibliográficos
Main Authors: Durgan, David J., Pulinilkunnil, Thomas, Villegas-Montoya, Carolina, Garvey, Merissa E., Frangogiannis, Nikolaos G., Michael, Lloyd H., Chow, Chi-Wing, Dyck, Jason R.B., Young, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021132/
https://ncbi.nlm.nih.gov/pubmed/20007913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.209346
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