IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

Graft versus host disease (GVHD), mediated by donor T cells, is a significant source of morbidity and mortality following allogeneic stem cell transplantation. Mesenchymal stem cells (MSC) can successfully treat ongoing graft versus host disease, presumably due to their ability to suppress donor T c...

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Detalhes bibliográficos
Main Authors: Polchert, David, Sobinsky, Justin, Douglas, GW, Kidd, Martha, Moadsiri, Ada, Reina, Eduardo, Genrich, Kristyn, Mehrotra, Swati, Setty, Suman, Smith, Brett, Bartholomew, Amelia
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021120/
https://ncbi.nlm.nih.gov/pubmed/18493986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200738129
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