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LC/MS evaluation of metabolism and membrane transport of bombesin peptides
Two bombsin peptides, GRPR agonist [Aca-QWAVGHLM-NH(2)] and antagonist [fQWAVGHL-NHEthyl] were evaluated. We employed the highly sensitive Waters Q-Tof Premier MS coupled with a UPLC system to identify the metabolites produced by rat hepatocytes or PC-3 human prostate cancer cells; and we utilized t...
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Hoofdauteurs: | , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2010
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020998/ https://ncbi.nlm.nih.gov/pubmed/20676905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-010-0696-y |
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