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Evaluation of Fluorine-labeled Gastrin-Releasing Peptide Receptor (GRPR) Agonists and Antagonists by LC/MS

An LC/MS method was used to evaluate 2-fluoropropionyl (FP) and 4-fluorobenzoyl (FB) modified bombsin peptides: GRPR agonist [Aca-QWAVGHLM-NH(2)] and antagonist [fQWAVGHL-NHEt], and their hydrophilic linker modified counterparts with the attachment of GGGRDN sequence. This study developed strategies...

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Detalhes bibliográficos
Main Authors: Ma, Ying, Yang, Min, Gao, Haokao, Niu, Gang, Yan, Yongjun, Lang, Lixin, Kiesewetter, Dale O., Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387330/
https://ncbi.nlm.nih.gov/pubmed/22354143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-012-1238-6
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