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PPARδ Activation Acts Cooperatively with 3-Phosphoinositide-Dependent Protein Kinase-1 to Enhance Mammary Tumorigenesis

Peroxisome proliferator-activated receptorδ (PPARδ) is a transcription factor that is associated with metabolic gene regulation and inflammation. It has been implicated in tumor promotion and in the regulation of 3-phosphoinositide-dependent kinase-1 (PDK1). PDK1 is a key regulator of the AGC protei...

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Detalles Bibliográficos
Main Authors: Pollock, Claire B., Yin, Yuzhi, Yuan, Hongyan, Zeng, Xiao, King, Sruthi, Li, Xin, Kopelovich, Levy, Albanese, Chris, Glazer, Robert I.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020974/
https://ncbi.nlm.nih.gov/pubmed/21297860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016215
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