Peroxisome proliferator-activated receptor δ (PPARδ) induces estrogen receptor-positive mammary neoplasia through an inflammatory and metabolic phenotype linked to mTor activation

The peroxisome proliferator-activated receptor-δ (PPARδ) regulates a multitude of physiological processes associated with glucose and lipid metabolism, inflammation and proliferation. One or more of these processes are potential risk factors for the ability of PPARδ agonists to promote tumorigenesis...

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Detalhes bibliográficos
Main Authors: Yuan, Hongyan, Lu, Jin, Xiao, Junfeng, Upadhyay, Geeta, Umans, Rachel, Kallakury, Bhaskar, Yin, Yuhzi, Fant, Michael E., Kopelovich, Levy, Glazer, Robert I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723355/
https://ncbi.nlm.nih.gov/pubmed/23811944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0322
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