The Chemopreventive Effect of Mifepristone on Mammary Tumorigenesis is Associated with an Anti-invasive and Anti-inflammatory Gene Signature

Progesterone receptor (PR) antagonists are potent antitumor agents in carcinogen and progestin-dependent mammary tumorigenesis models through both PR and non-PR-mediated mechanisms. The PR antagonist mifepristone/RU486 has been used primarily as an abortifacient possessing high affinity for both the...

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Detaylı Bibliyografya
Asıl Yazarlar: Yuan, Hongyan, Upadhyay, Geeta, Lu, Jin, Kopelovich, Levy, Glazer, Robert I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437618/
https://ncbi.nlm.nih.gov/pubmed/22427346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0526
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