Cross-Regulation between Oncogenic BRAF(V600E) Kinase and the MST1 Pathway in Papillary Thyroid Carcinoma

BACKGROUND: The BRAF(V600E) mutation leading to constitutive signaling of MEK-ERK pathways causes papillary thyroid cancer (PTC). Ras association domain family 1A (RASSF1A), which is an important regulator of MST1 tumor suppressor pathways, is inactivated by hypermethylation of its promoter region i...

Full description

Saved in:
Bibliographic Details
Main Authors: Lee, Seong Jin, Lee, Min Hee, Kim, Dong Wook, Lee, SeongEun, Huang, Songmei, Ryu, Min Jeong, Kim, Yong Kyung, Kim, Sung Jin, Kim, Soung Jung, Hwang, Jung Hwan, Oh, Sangphil, Cho, Heeyeong, Kim, Jin Man, Lim, Dae-Sik, Jo, Young Suk, Shong, Minho
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020965/
https://ncbi.nlm.nih.gov/pubmed/21249150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016180
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items