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Homodimerization of Nemo-like kinase is essential for activation and nuclear localization
Nemo-like kinase (NLK) is an evolutionarily conserved protein kinase that phosphorylates several transcription factors. However, the molecular mechanisms that regulate NLK activity have been poorly understood. Here we show that homodimerization of NLK is required for its activation and nuclear local...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020921/ https://ncbi.nlm.nih.gov/pubmed/21118996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-07-0605 |
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