STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFβ-activated kinase 1 for STAT3 Ser-727 phosphorylation

Signal transducer and activator of transcription 3 (STAT3) is activated by the IL-6 family of cytokines and growth factors. STAT3 requires phosphorylation on Ser-727, in addition to tyrosine phosphorylation on Tyr-705, to be transcriptionally active. In IL-6 signaling, the two major pathways that de...

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Detalhes bibliográficos
Main Authors: Kojima, Hirotada, Sasaki, Takanori, Ishitani, Tohru, Iemura, Shun-ichiro, Zhao, Hong, Kaneko, Shuhei, Kunimoto, Hiroyuki, Natsume, Tohru, Matsumoto, Kunihiro, Nakajima, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC555521/
https://ncbi.nlm.nih.gov/pubmed/15764709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500679102
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