Aberrant Estrogen Regulation of PEMT Results in Choline Deficiency-associated Liver Dysfunction

When dietary choline is restricted, most men and postmenopausal women develop multiorgan dysfunction marked by hepatic steatosis (choline deficiency syndrome (CDS)). However, a significant subset of premenopausal women is protected from CDS. Because hepatic PEMT (phosphatidylethanolamine N-methyltra...

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Main Authors: Resseguie, Mary E., da Costa, Kerry-Ann, Galanko, Joseph A., Patel, Mukund, Davis, Ian J., Zeisel, Steven H.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
主題:
Gene Regulation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020773/
https://ncbi.nlm.nih.gov/pubmed/21059658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106922
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