Opposing Actions of Extracellular Signal-regulated Kinase (ERK) and Signal Transducer and Activator of Transcription 3 (STAT3) in Regulating Microtubule Stabilization during Cardiac Hypertrophy

Excessive proliferation and stabilization of the microtubule (MT) array in cardiac myocytes can accompany pathological cardiac hypertrophy, but the molecular control of these changes remains poorly characterized. In this study, we examined MT stabilization in two independent murine models of heart f...

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Autori principali: Ng, Dominic C. H., Ng, Ivan H. W., Yeap, Yvonne Y. C., Badrian, Bahareh, Tsoutsman, Tatiana, McMullen, Julie R., Semsarian, Christopher, Bogoyevitch, Marie A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020766/
https://ncbi.nlm.nih.gov/pubmed/21056972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.128157
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