Opposing roles for JNK and Aurora A in regulating the association of WDR62 with spindle microtubules

WD40-repeat protein 62 (WDR62) is a spindle pole protein required for normal cell division and neuroprogenitor differentiation during brain development. Microcephaly-associated mutations in WDR62 lead to mitotic mislocalization, highlighting a crucial requirement for precise WDR62 spatiotemporal dis...

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Dettagli Bibliografici
Pubblicato in:J Cell Sci
Autori principali: Lim, Nicholas R., Yeap, Yvonne Y. C., Zhao, Teresa T., Yip, Yan Y., Wong, Shu C., Xu, Dan, Ang, Ching-Seng, Williamson, Nicholas A., Xu, Zhiheng, Bogoyevitch, Marie A., Ng, Dominic C. H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311131/
https://ncbi.nlm.nih.gov/pubmed/25501809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.157537
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