Phosphorylation of Phosphatidate Phosphatase Regulates Its Membrane Association and Physiological Functions in Saccharomyces cerevisiae: IDENTIFICATION OF SER(602), THR(723), AND SER(744) AS THE SITES PHOSPHORYLATED BY CDC28 (CDK1)-ENCODED CYCLIN-DEPENDENT KINASE

The Saccharomyces cerevisiae PAH1-encoded phosphatidate phosphatase (PAP) catalyzes the penultimate step in the synthesis of triacylglycerol and plays a role in the transcriptional regulation of phospholipid synthesis genes. PAP is phosphorylated at multiple Ser and Thr residues and is dephosphoryla...

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Bibliographische Detailangaben
Hauptverfasser: Choi, Hyeon-Son, Su, Wen-Min, Morgan, Jeanelle M., Han, Gil-Soo, Xu, Zhi, Karanasios, Eleftherios, Siniossoglou, Symeon, Carman, George M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Lipids
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020757/
https://ncbi.nlm.nih.gov/pubmed/21081492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155598
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