Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes

TAR DNA-binding protein 43 (TDP-43) is associated with a spectrum of neurodegenerative diseases. Although TDP-43 resembles heterogeneous nuclear ribonucleoproteins, its RNA targets and physiological protein partners remain unknown. Here we identify RNA targets of TDP-43 from cortical neurons by RNA...

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Detalhes bibliográficos
Main Authors: Sephton, Chantelle F., Cenik, Can, Kucukural, Alper, Dammer, Eric B., Cenik, Basar, Han, YuHong, Dewey, Colleen M., Roth, Frederick P., Herz, Joachim, Peng, Junmin, Moore, Melissa J., Yu, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020728/
https://ncbi.nlm.nih.gov/pubmed/21051541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190884
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