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Expression of a transgene encoding mutant p193/CUL7 preserves cardiac function and limits infarct expansion after myocardial infarction

OBJECTIVE: Transgenic mice expressing the dominant interfering p193 protein in cardiomyocytes (MHC-1152stop mice) exhibit an induction of cell cycle activity and altered remodeling following experimental myocardial infarction (MI). We hypothesized that the altered remodeling would result in improved...

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Detalhes bibliográficos
Main Authors: Hassink, RJ, Nakajima, H, Nakajima, HO, Doevendans, PA, Field, LJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020667/
https://ncbi.nlm.nih.gov/pubmed/19435717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2008.150128
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