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Expression of a transgene encoding mutant p193/CUL7 preserves cardiac function and limits infarct expansion after myocardial infarction
OBJECTIVE: Transgenic mice expressing the dominant interfering p193 protein in cardiomyocytes (MHC-1152stop mice) exhibit an induction of cell cycle activity and altered remodeling following experimental myocardial infarction (MI). We hypothesized that the altered remodeling would result in improved...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020667/ https://ncbi.nlm.nih.gov/pubmed/19435717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2008.150128 |
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