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Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP

In eukaryotes, polyadenylation of pre-mRNA plays an essential role in the initiation step of protein synthesis, as well as in the export and stability of mRNAs. Poly(A) polymerase, the enzyme at the heart of the polyadenylation machinery, is a template-independent RNA polymerase which specifically i...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Martin, Georges, Keller, Walter, Doublié, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10944102/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.16.4193
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