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Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP

In eukaryotes, polyadenylation of pre-mRNA plays an essential role in the initiation step of protein synthesis, as well as in the export and stability of mRNAs. Poly(A) polymerase, the enzyme at the heart of the polyadenylation machinery, is a template-independent RNA polymerase which specifically i...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Martin, Georges, Keller, Walter, Doublié, Sylvie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC302044/
https://ncbi.nlm.nih.gov/pubmed/10944102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.16.4193
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