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Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP
In eukaryotes, polyadenylation of pre-mRNA plays an essential role in the initiation step of protein synthesis, as well as in the export and stability of mRNAs. Poly(A) polymerase, the enzyme at the heart of the polyadenylation machinery, is a template-independent RNA polymerase which specifically i...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302044/ https://ncbi.nlm.nih.gov/pubmed/10944102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.16.4193 |
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