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Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP

In eukaryotes, polyadenylation of pre-mRNA plays an essential role in the initiation step of protein synthesis, as well as in the export and stability of mRNAs. Poly(A) polymerase, the enzyme at the heart of the polyadenylation machinery, is a template-independent RNA polymerase which specifically i...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Martin, Georges, Keller, Walter, Doublié, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2000
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10944102/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.16.4193
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